Seeing is Believing

So many questions surround the creation of and interaction with artwork. 
Questions that move beyond the creation and mere technical skills of a particular artist. 
In his book, Interaction of Color, Josef Albers, 1963 one key element of artwork, colour, is discussed. In his introduction he points out that "color deceives continually".  

So, I wonder, once colour is introduced into a work is seeing really believing?